In Malawi, innovative models have been developed to optimize the efficiency of HIV service delivery in order to scale up access to treatment. In particular, three key models of differentiated care have emerged: multi-month prescriptions; fast-track drug refills; and community ART groups. In collaboration with the Ministry of Health of Malawi, CHAI conducted a mixed methods process evaluation that assessed the extent to which patients in Malawi are differentiated based on clinical stability and described the characteristics and costs of the models.